Cargando…
The toposiomerase IIIalpha-RMI1-RMI2 complex orients human Bloom’s syndrome helicase for efficient disruption of D-loops
Homologous recombination (HR) is a ubiquitous and efficient process that serves the repair of severe forms of DNA damage and the generation of genetic diversity during meiosis. HR can proceed via multiple pathways with different outcomes that may aid or impair genome stability and faithful inheritan...
Autores principales: | Harami, Gábor M., Pálinkás, János, Seol, Yeonee, Kovács, Zoltán J., Gyimesi, Máté, Harami-Papp, Hajnalka, Neuman, Keir C., Kovács, Mihály |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813930/ https://www.ncbi.nlm.nih.gov/pubmed/35115525 http://dx.doi.org/10.1038/s41467-022-28208-9 |
Ejemplares similares
-
RecQ helicase triggers a binding mode change in the SSB–DNA complex to efficiently initiate DNA unwinding
por: Mills, Maria, et al.
Publicado: (2017) -
Homology sensing via non-linear amplification of sequence-dependent pausing by RecQ helicase
por: Seol, Yeonee, et al.
Publicado: (2019) -
Complex activities of the human Bloom's syndrome helicase are encoded in a core region comprising the RecA and Zn-binding domains
por: Gyimesi, Máté, et al.
Publicado: (2012) -
The HRDC domain of E. coli RecQ helicase controls single-stranded DNA translocation and double-stranded DNA unwinding rates without affecting mechanoenzymatic coupling
por: Harami, Gábor M., et al.
Publicado: (2015) -
Bloom syndrome helicase contributes to germ line development and longevity in zebrafish
por: Annus, Tamás, et al.
Publicado: (2022)