Cargando…

Intracellular CYTL1, a novel tumor suppressor, stabilizes NDUFV1 to inhibit metabolic reprogramming in breast cancer

Loss-of-function mutations frequently occur in tumor suppressor genes, i.e., p53, during the malignant progression of various cancers. Whether any intrinsic suppressor carries a rare mutation is largely unknown. Here, we demonstrate that intracellular cytokine-like protein 1 (CYTL1) plays a key role...

Descripción completa

Detalles Bibliográficos
Autores principales: Xue, Wenwen, Li, Xin, Li, Wuhao, Wang, Yixuan, Jiang, Chengfei, Zhou, Lin, Gao, Jian, Yu, Ying, Shen, Yan, Xu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813937/
https://www.ncbi.nlm.nih.gov/pubmed/35115484
http://dx.doi.org/10.1038/s41392-021-00856-1