Reactive Astrocytes Contribute to Alzheimer’s Disease-Related Neurotoxicity and Synaptotoxicity in a Neuron-Astrocyte Co-culture Assay

Pathological hallmarks of Alzheimer’s disease (AD) include deposition and accumulation of amyloid- β (Aβ), neurofibrillary tangle formation, and neuronal loss. Pathogenesis of presymptomatic disease stages remains elusive, although studies suggest that the early structural and functional alterations...

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Detalles Bibliográficos
Autores principales: Wasilewski, David, Villalba-Moreno, Nelson David, Stange, Inke, Glatzel, Markus, Sepulveda-Falla, Diego, Krasemann, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813976/
https://www.ncbi.nlm.nih.gov/pubmed/35126055
http://dx.doi.org/10.3389/fncel.2021.739411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813976/
https://www.ncbi.nlm.nih.gov/pubmed/35126055
http://dx.doi.org/10.3389/fncel.2021.739411

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