Cargando…

Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice

Efficacy of monoclonal antibodies against calcitonin gene-related peptide (CGRP) or its receptor (calcitonin receptor-like receptor/receptor activity modifying protein-1, CLR/RAMP1) implicates peripherally-released CGRP in migraine pain. However, the site and mechanism of CGRP-evoked peripheral pain...

Descripción completa

Detalles Bibliográficos
Autores principales: De Logu, Francesco, Nassini, Romina, Hegron, Alan, Landini, Lorenzo, Jensen, Dane D., Latorre, Rocco, Ding, Julia, Marini, Matilde, Souza Monteiro de Araujo, Daniel, Ramírez-Garcia, Paulina, Whittaker, Michael, Retamal, Jeffri, Titiz, Mustafa, Innocenti, Alessandro, Davis, Thomas P., Veldhuis, Nicholas, Schmidt, Brian L., Bunnett, Nigel W., Geppetti, Pierangelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813987/
https://www.ncbi.nlm.nih.gov/pubmed/35115501
http://dx.doi.org/10.1038/s41467-022-28204-z