Cargando…

Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice

Efficacy of monoclonal antibodies against calcitonin gene-related peptide (CGRP) or its receptor (calcitonin receptor-like receptor/receptor activity modifying protein-1, CLR/RAMP1) implicates peripherally-released CGRP in migraine pain. However, the site and mechanism of CGRP-evoked peripheral pain...

Descripción completa

Detalles Bibliográficos
Autores principales:	De Logu, Francesco, Nassini, Romina, Hegron, Alan, Landini, Lorenzo, Jensen, Dane D., Latorre, Rocco, Ding, Julia, Marini, Matilde, Souza Monteiro de Araujo, Daniel, Ramírez-Garcia, Paulina, Whittaker, Michael, Retamal, Jeffri, Titiz, Mustafa, Innocenti, Alessandro, Davis, Thomas P., Veldhuis, Nicholas, Schmidt, Brian L., Bunnett, Nigel W., Geppetti, Pierangelo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813987/ https://www.ncbi.nlm.nih.gov/pubmed/35115501 http://dx.doi.org/10.1038/s41467-022-28204-z

Ejemplares similares

Acetaldehyde via CGRP receptor and TRPA1 in Schwann cells mediates ethanol-evoked periorbital mechanical allodynia in mice: relevance for migraine
por: Landini, Lorenzo, et al.
Publicado: (2023)

Migraine-provoking substances evoke periorbital allodynia in mice
por: De Logu, Francesco, et al.
Publicado: (2019)

TRPA1 Role in Inflammatory Disorders: What Is Known So Far?
por: Landini, Lorenzo, et al.
Publicado: (2022)

TRP Channels in Cancer: Signaling Mechanisms and Translational Approaches
por: Marini, Matilde, et al.
Publicado: (2023)

Neuropathic-like Nociception and Spinal Cord Neuroinflammation Are Dependent on the TRPA1 Channel in Multiple Sclerosis Models in Mice
por: Dalenogare, Diéssica Padilha, et al.
Publicado: (2023)

Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice
por: De Logu, Francesco, et al.
Publicado: (2017)

The TRPA1 Channel Amplifies the Oxidative Stress Signal in Melanoma
por: De Logu, Francesco, et al.
Publicado: (2021)

Periorbital Nociception in a Progressive Multiple Sclerosis Mouse Model Is Dependent on TRPA1 Channel Activation
por: Dalenogare, Diéssica Padilha, et al.
Publicado: (2021)

CGRP receptors and TRP channels in migraine
por: Geppetti, Pierangelo, et al.
Publicado: (2015)

TRPA1 as a therapeutic target for nociceptive pain
por: Souza Monteiro de Araujo, Daniel, et al.
Publicado: (2020)

Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief
por: Hegron, Alan, et al.
Publicado: (2023)

Oxidative stress mediates thalidomide-induced pain by targeting peripheral TRPA1 and central TRPV4
por: De Logu, Francesco, et al.
Publicado: (2020)

The Role of TRPA1 in Skin Physiology and Pathology
por: Maglie, Roberto, et al.
Publicado: (2021)

TRPA1/NOX in the soma of trigeminal ganglion neurons mediates migraine-related pain of glyceryl trinitrate in mice
por: Marone, Ilaria Maddalena, et al.
Publicado: (2018)

TRPA1 mediates the antinociceptive properties of the constituent of Crocus sativus L., safranal
por: Li Puma, Simone, et al.
Publicado: (2019)

Mice expressing fluorescent PAR(2) reveal that endocytosis mediates colonic inflammation and pain
por: Latorre, Rocco, et al.
Publicado: (2022)

Tetramethylpyrazine attenuates periorbital allodynia and neuroinflammation in a model of traumatic brain injury
por: Wang, Zhijing, et al.
Publicado: (2017)

Transient receptor potential ankyrin 1 contributes to somatic pain hypersensitivity in experimental colitis
por: Jain, Piyush, et al.
Publicado: (2020)

TRPA1 mediates damage of the retina induced by ischemia and reperfusion in mice
por: Souza Monteiro de Araújo, Daniel, et al.
Publicado: (2020)

Long-Term Effectiveness of Three Anti-CGRP Monoclonal Antibodies in Resistant Chronic Migraine Patients Based on the MIDAS score
por: Iannone, Luigi Francesco, et al.
Publicado: (2022)

CGRP and migraine: neurogenic inflammation revisited
por: Geppetti, P., et al.
Publicado: (2005)

A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes
por: Mai, Quynh N., et al.
Publicado: (2021)

ABHD6 and MAGL control 2-AG levels in the PAG and allodynia in a CSD-induced periorbital model of headache
por: Liktor-Busa, Erika, et al.
Publicado: (2023)

Internalized GPCRs as Potential Therapeutic Targets for the Management of Pain
por: Retamal, Jeffri S., et al.
Publicado: (2019)

Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1
por: Fusi, Camilla, et al.
Publicado: (2014)

Periorbital Noise
por: Hantson, Philippe, et al.
Publicado: (2009)

Periorbital dirofilariasis
por: Wiwanitkit, Somsri, et al.
Publicado: (2014)

Periorbital Richter Syndrome
por: Gorman, Mark, et al.
Publicado: (2015)

Periorbital Varicella Gangrenosa
por: Nayak, Surajit, et al.
Publicado: (2016)

Metastatic Esophageal Squamous Cell Carcinoma to the Orbit and Periorbit Masquerading as Periorbital Abscess
por: Lee, Ja Young, et al.
Publicado: (2010)

CGRP and CGRP receptors in human and rhesus monkey cerebellum
por: Eftekhari, S, et al.
Publicado: (2013)

Co- transplantation of Bone Marrow Stromal Cells with Schwann Cells Evokes Mechanical Allodynia in the Contusion Model of Spinal Cord Injury in Rats
por: Pourheydar, Bagher, et al.
Publicado: (2012)

Mechanical allodynia
por: Lolignier, Stéphane, et al.
Publicado: (2014)

CGRP in migraine
por: Tfelt-Hansen, Peer, et al.
Publicado: (2009)

CGRP and migraine
por: Cauchi, M., et al.
Publicado: (2016)

Fusion of Enveloped Viruses in Endosomes
por: White, Judith M., et al.
Publicado: (2016)

A Fast and Automated Melanin-bleaching Method for Histopathologic Evaluation of Pigmented Melanoma Tissues
por: Ugolini, Filippo, et al.
Publicado: (2022)

Abstract: The Frequency of Periorbital Asymmetry
por: Son, Ji, et al.
Publicado: (2017)

Postictal Periorbital Petechial Rash
por: Yoshihara, Akioh, et al.
Publicado: (2017)

Nodular Fasciitis of the Periorbital Area
por: Lee, Yoon-Jae, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_srdc3rnb9k76kbaembvp6ojobv