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Bdh1 overexpression ameliorates hepatic injury by activation of Nrf2 in a MAFLD mouse model

In 2020, a group of experts officially suggested metabolic dysfunction associated with fatty liver disease “MAFLD” as a more appropriate overarching term than NAFLD, indicating the key role of metabolism in fatty liver disease. Bdh1, as the rate-limiting enzyme of ketone metabolism, acts as an impor...

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Detalles Bibliográficos
Autores principales: Xu, Bu-tuo, Teng, Fang-yuan, Wu, Qi, Wan, Sheng-rong, Li, Xin-yue, Tan, Xiao-zhen, Xu, Yong, Jiang, Zong-zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814004/
https://www.ncbi.nlm.nih.gov/pubmed/35115498
http://dx.doi.org/10.1038/s41420-022-00840-w