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Bdh1 overexpression ameliorates hepatic injury by activation of Nrf2 in a MAFLD mouse model
In 2020, a group of experts officially suggested metabolic dysfunction associated with fatty liver disease “MAFLD” as a more appropriate overarching term than NAFLD, indicating the key role of metabolism in fatty liver disease. Bdh1, as the rate-limiting enzyme of ketone metabolism, acts as an impor...
Autores principales: | Xu, Bu-tuo, Teng, Fang-yuan, Wu, Qi, Wan, Sheng-rong, Li, Xin-yue, Tan, Xiao-zhen, Xu, Yong, Jiang, Zong-zhe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814004/ https://www.ncbi.nlm.nih.gov/pubmed/35115498 http://dx.doi.org/10.1038/s41420-022-00840-w |
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