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Oncogenic E3 ubiquitin ligase NEDD4 binds to KLF8 and regulates the microRNA-132/NRF2 axis in bladder cancer

The neuronally expressed developmentally downregulated 4 (NEDD4) gene encodes a ubiquitin ligase that targets the epithelial sodium channel for degradation and has been implicated in tumor growth in various cancers. Hence, in this study, we intended to characterize the functional relevance of the NE...

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Detalles Bibliográficos
Autores principales: Mao, Minghuan, Yang, Liang, Hu, Jingyao, Liu, Bing, Zhang, Xiling, Liu, Yili, Wang, Ping, Li, Hangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814007/
https://www.ncbi.nlm.nih.gov/pubmed/35031788
http://dx.doi.org/10.1038/s12276-021-00663-2