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Oncogenic E3 ubiquitin ligase NEDD4 binds to KLF8 and regulates the microRNA-132/NRF2 axis in bladder cancer
The neuronally expressed developmentally downregulated 4 (NEDD4) gene encodes a ubiquitin ligase that targets the epithelial sodium channel for degradation and has been implicated in tumor growth in various cancers. Hence, in this study, we intended to characterize the functional relevance of the NE...
Autores principales: | Mao, Minghuan, Yang, Liang, Hu, Jingyao, Liu, Bing, Zhang, Xiling, Liu, Yili, Wang, Ping, Li, Hangyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814007/ https://www.ncbi.nlm.nih.gov/pubmed/35031788 http://dx.doi.org/10.1038/s12276-021-00663-2 |
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