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Molecular insights into the interaction of HPV-16 E6 variants against MAGI-1 PDZ1 domain

Oncogenic protein E6 from Human Papilloma Virus 16 (HPV-16) mediates the degradation of Membrane-associated guanylate kinase with inverted domain structure-1 (MAGI-1), throughout the interaction of its protein binding motif (PBM) with the Discs-large homologous regions 1 (PDZ1) domain of MAG1-1. Gen...

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Detalles Bibliográficos
Autores principales: Araujo-Arcos, Lilian Esmeralda, Montaño, Sarita, Bello-Rios, Ciresthel, Garibay-Cerdenares, Olga Lilia, Leyva-Vázquez, Marco Antonio, Illades-Aguiar, Berenice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814009/
https://www.ncbi.nlm.nih.gov/pubmed/35115618
http://dx.doi.org/10.1038/s41598-022-05995-1