Mitochondrial protein import determines lifespan through metabolic reprogramming and de novo serine biosynthesis

Sustained mitochondrial fitness relies on coordinated biogenesis and clearance. Both processes are regulated by constant targeting of proteins into the organelle. Thus, mitochondrial protein import sets the pace for mitochondrial abundance and function. However, our understanding of mitochondrial pr...

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Detalles Bibliográficos
Autores principales: Lionaki, Eirini, Gkikas, Ilias, Daskalaki, Ioanna, Ioannidi, Maria-Konstantina, Klapa, Maria I., Tavernarakis, Nektarios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814026/
https://www.ncbi.nlm.nih.gov/pubmed/35115503
http://dx.doi.org/10.1038/s41467-022-28272-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814026/
https://www.ncbi.nlm.nih.gov/pubmed/35115503
http://dx.doi.org/10.1038/s41467-022-28272-1

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