Synthesis and characterization of novel combretastatin analogues of 1,1-diaryl vinyl sulfones, with antiproliferative potential via in-silico and in-vitro studies

Novel 1,1-diaryl vinyl-sulfones analogues of combretastatin CA-4 were synthesized via Suzuki–Miyaura coupling method and screened for in-vitro antiproliferative activity against four human cancer cell lines: MDA-MB 231(breast cancer), HeLa (cervical cancer), A549 (lung cancer), and IMR-32 (neuroblas...

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Detalles Bibliográficos
Autores principales: Egharevba, Godshelp O., Kamal, Ahmed, Dosumu, Omotayo O., Routhu, Sunitha, Fadare, Olatomide A., Oguntoye, Stephen O., Njinga, Stanislaus N., Oluyori, Abimbola P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814031/
https://www.ncbi.nlm.nih.gov/pubmed/35115623
http://dx.doi.org/10.1038/s41598-022-05958-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814031/
https://www.ncbi.nlm.nih.gov/pubmed/35115623
http://dx.doi.org/10.1038/s41598-022-05958-6

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