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Mouse models of patent ductus arteriosus (PDA) and their relevance for human PDA

The ductus arteriosus (DA) is a unique fetal vascular shunt, which allows blood to bypass the developing lungs in utero. After birth, changes in complex signaling pathways lead to constriction and permanent closure of the DA. The persistent patency of the DA (PDA) is a common disorder in preterm inf...

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Detalles Bibliográficos
Autores principales: Yarboro, Michael T., Gopal, Srirupa H., Su, Rachel L., Morgan, Thomas M., Reese, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814064/
https://www.ncbi.nlm.nih.gov/pubmed/34350653
http://dx.doi.org/10.1002/dvdy.408