Atypical Hemolytic Uremic Syndrome-Associated FHR1 Isoform FHR1*B Enhances Complement Activation and Inflammation

Atypical hemolytic uremic syndrome (aHUS) is a rare but severe type of thrombotic microangiopathy that is triggered by the abnormal activation of the alternative complement pathway. Previous studies have reported that three completely linked coding variants of CFHR1 form two haplotypes, namely, CFHR...

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Detalles Bibliográficos
Autores principales: Xu, Boyang, Kang, Yuqi, Du, Yujing, Guo, Weiyi, Zhu, Li, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814109/
https://www.ncbi.nlm.nih.gov/pubmed/35126388
http://dx.doi.org/10.3389/fimmu.2022.755694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814109/
https://www.ncbi.nlm.nih.gov/pubmed/35126388
http://dx.doi.org/10.3389/fimmu.2022.755694

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