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Dual inhibition of anti-apoptotic proteins BCL-XL and MCL-1 enhances cytotoxicity of Nasopharyngeal carcinoma cells

One of the many strategies that cancer cells evade death is through up-regulation of the BCL-2 anti-apoptotic proteins. Hence, these proteins have become attractive therapeutic targets. Given that different cell populations rely on different anti-apoptotic proteins for survival, it is crucial to det...

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Detalles Bibliográficos
Autores principales: Abdul Rahman, Siti Fairus, Azlan, Azali, Lo, Kwok-Wai, Azzam, Ghows, Mohana-Kumaran, Nethia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814124/
https://www.ncbi.nlm.nih.gov/pubmed/35201512
http://dx.doi.org/10.1007/s12672-022-00470-9