Hypothalamic expression of huntingtin causes distinct metabolic changes in Huntington's disease mice

OBJECTIVE: In Huntington's disease (HD), the disease-causing huntingtin (HTT) protein is ubiquitously expressed and causes both central and peripheral pathology. In clinical HD, a higher body mass index has been associated with slower disease progression, indicating the role of metabolic change...

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Detalles Bibliográficos
Autores principales: Dickson, Elna, Soylu-Kucharz, Rana, Petersén, Åsa, Björkqvist, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814380/
https://www.ncbi.nlm.nih.gov/pubmed/35007790
http://dx.doi.org/10.1016/j.molmet.2022.101439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814380/
https://www.ncbi.nlm.nih.gov/pubmed/35007790
http://dx.doi.org/10.1016/j.molmet.2022.101439

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