Disruption of STIM1-mediated Ca(2+) sensing and energy metabolism in adult skeletal muscle compromises exercise tolerance, proteostasis, and lean mass

OBJECTIVE: Stromal interaction molecule 1 (STIM1) is a single-pass transmembrane endoplasmic/sarcoplasmic reticulum (E/SR) protein recognized for its role in a store operated Ca(2+) entry (SOCE), an ancient and ubiquitous signaling pathway. Whereas STIM1 is known to be indispensable during developme...

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Detalles Bibliográficos
Autores principales: Wilson, Rebecca J., Lyons, Scott P., Koves, Timothy R., Bryson, Victoria G., Zhang, Hengtao, Li, TianYu, Crown, Scott B., Ding, Jin-Dong, Grimsrud, Paul A., Rosenberg, Paul B., Muoio, Deborah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814391/
https://www.ncbi.nlm.nih.gov/pubmed/34979330
http://dx.doi.org/10.1016/j.molmet.2021.101429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814391/
https://www.ncbi.nlm.nih.gov/pubmed/34979330
http://dx.doi.org/10.1016/j.molmet.2021.101429

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