Long Non-coding RNA MALAT1 Is Depleted With Age in Skeletal Muscle in vivo and MALAT1 Silencing Increases Expression of TGF-β1 in vitro

Long non-coding RNAs (lncRNAs) are thought to function as “sponges” for microRNAs, but a role for such competing endogenous RNAs (ceRNAs) in muscle aging is not well understood. We therefore examined in skeletal muscles of young (4–6 months) and aged (22–24) male and female mice the expression of ln...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruan, Ling, Mendhe, Bharati, Parker, Emily, Kent, Andrew, Isales, Carlos M., Hill, William D., McGee-Lawrence, Meghan, Fulzele, Sadanand, Hamrick, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814451/
https://www.ncbi.nlm.nih.gov/pubmed/35126169
http://dx.doi.org/10.3389/fphys.2021.742004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814451/
https://www.ncbi.nlm.nih.gov/pubmed/35126169
http://dx.doi.org/10.3389/fphys.2021.742004

Ejemplares similares