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Inhibitors of Human 5-Lipoxygenase Potently Interfere With Prostaglandin Transport

5-Lipoxygenase (5-LO) is the key enzyme in the formation of pro-inflammatory leukotrienes (LT) which play an important role in a number of inflammatory diseases. Accordingly, 5-LO inhibitors are frequently used to study the role of 5-LO and LT in models of inflammation and cancer. Interestingly, the...

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Detalles Bibliográficos
Autores principales: Kahnt, Astrid S., Angioni, Carlo, Göbel, Tamara, Hofmann, Bettina, Roos, Jessica, Steinbrink, Svenja D., Rörsch, Florian, Thomas, Dominique, Geisslinger, Gerd, Zacharowski, Kai, Grösch, Sabine, Steinhilber, Dieter, Maier, Thorsten J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814463/
https://www.ncbi.nlm.nih.gov/pubmed/35126121
http://dx.doi.org/10.3389/fphar.2021.782584