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Identification of an Aptamer With Binding Specificity to Tumor-Homing Myeloid-Derived Suppressor Cells
Myeloid-derived suppressor cells (MDSCs) play a critical role in tumor growth and metastasis. Since they constantly infiltrate into the tumor tissue, these cells are considered as an ideal carrier for tumor-targeted drug delivery. We recently identified a DNA-based thioaptamer (T1) with tumor accumu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814529/ https://www.ncbi.nlm.nih.gov/pubmed/35126104 http://dx.doi.org/10.3389/fphar.2021.752934 |