Cargando…

Identification of an Aptamer With Binding Specificity to Tumor-Homing Myeloid-Derived Suppressor Cells

Myeloid-derived suppressor cells (MDSCs) play a critical role in tumor growth and metastasis. Since they constantly infiltrate into the tumor tissue, these cells are considered as an ideal carrier for tumor-targeted drug delivery. We recently identified a DNA-based thioaptamer (T1) with tumor accumu...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Shaohui, Welte, Thomas, Mai, Junhua, Liu, Yongbin, Ramirez, Maricela, Shen, Haifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814529/
https://www.ncbi.nlm.nih.gov/pubmed/35126104
http://dx.doi.org/10.3389/fphar.2021.752934