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Relative Efficacy of (225)Ac-PSMA-617 and (177)Lu-PSMA-617 in Prostate Cancer Based on Subcellular Dosimetry

OBJECTIVES: Radionuclide therapy targeting prostate-specific membrane antigen (PSMA) with alpha-emitting (225)Ac-PSMA-617 has shown clinical efficacy even in cases of failed therapy with beta-emitting (177)Lu-PSMA-617. We investigated the efficacy of (225)Ac-PSMA-617 relative to (177)Lu-PSMA-617 usi...

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Detalles Bibliográficos
Autor principal: Lee, Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814544/
https://www.ncbi.nlm.nih.gov/pubmed/35114745
http://dx.doi.org/10.4274/mirt.galenos.2021.63308