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Prediction of Residue-specific Contributions to Binding and Thermal Stability Using Yeast Surface Display
Accurate prediction of residue burial as well as quantitative prediction of residue-specific contributions to protein stability and activity is challenging, especially in the absence of experimental structural information. This is important for prediction and understanding of disease causing mutatio...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814602/ https://www.ncbi.nlm.nih.gov/pubmed/35127820 http://dx.doi.org/10.3389/fmolb.2021.800819 |