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m6A demethylation of cytidine deaminase APOBEC3B mRNA orchestrates arsenic-induced mutagenesis

The cytidine deaminase APOBEC3B (A3B) is an endogenous inducer of somatic mutations and causes chromosomal instability by converting cytosine to uracil in single-stranded DNA. Therefore, identification of factors and mechanisms that mediate A3B expression will be helpful for developing therapeutic a...

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Detalles Bibliográficos
Autores principales: Gao, Ming, Qi, Zijuan, Feng, Wenya, Huang, Hongyang, Xu, Zhijie, Dong, Zheng, Xu, Ming, Han, Jinxiang, Kloeber, Jake A., Huang, Jinzhou, Lou, Zhenkun, Liu, Sijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814665/
https://www.ncbi.nlm.nih.gov/pubmed/34998823
http://dx.doi.org/10.1016/j.jbc.2022.101563