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Structural insights into apoptotic regulation of human Bfk as a novel Bcl-2 family member

Bcl-2 family kin (Bfk), also known as Bcl-2-like 15, plays an essential role in regulating apoptosis by eliciting weak pro-apoptotic responses in the gastrointestinal tract. Human Bfk is a novel Bcl-2 family protein owing to its unique domain composition involving BH2 and BH3. However, the molecular...

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Detalles Bibliográficos
Autores principales: Jang, Dong Man, Oh, Eun Kyung, Hahn, Hyunggu, Kim, Hyoun Sook, Han, Byung Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814693/
https://www.ncbi.nlm.nih.gov/pubmed/35140891
http://dx.doi.org/10.1016/j.csbj.2022.01.023