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Upregulation of CD14 in mesenchymal stromal cells accelerates lipopolysaccharide-induced response and enhances antibacterial properties

Mesenchymal stromal cells (MSCs) have broad-ranging therapeutic properties, including the ability to inhibit bacterial growth and resolve infection. However, the genetic mechanisms regulating these antibacterial properties in MSCs are largely unknown. Here, we utilized a systems-based approach to co...

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Detalles Bibliográficos
Autores principales: Hirakawa, Matthew P., Tjahjono, Nikki, Light, Yooli K., Celebi, Aleyna N., Celebi, Nisa N., Chintalapudi, Prem, Butler, Kimberly S., Branda, Steven S., Krishnakumar, Raga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814754/
https://www.ncbi.nlm.nih.gov/pubmed/35141503
http://dx.doi.org/10.1016/j.isci.2022.103759