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CLSPCOL rescues Alzheimer’s disease mouse models

Calmodulin-like skin protein (CLSP) inhibits Alzheimer’s disease (AD)-related neurotoxicity. The activity of CLSP is reduced in AD. To restore the CLSP activity, we developed a hybrid peptide named CLSPCOL, consisting of CLSP(1–61) and the collagen-homologous region (COL) of adiponectin. It was prev...

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Detalles Bibliográficos
Autores principales: Kusakari, Shinya, Nawa, Mikiro, Hashimoto, Yuichi, Matsuoka, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814939/
https://www.ncbi.nlm.nih.gov/pubmed/35178248
http://dx.doi.org/10.1515/tnsci-2022-0209