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CLSPCOL rescues Alzheimer’s disease mouse models
Calmodulin-like skin protein (CLSP) inhibits Alzheimer’s disease (AD)-related neurotoxicity. The activity of CLSP is reduced in AD. To restore the CLSP activity, we developed a hybrid peptide named CLSPCOL, consisting of CLSP(1–61) and the collagen-homologous region (COL) of adiponectin. It was prev...
Autores principales: | Kusakari, Shinya, Nawa, Mikiro, Hashimoto, Yuichi, Matsuoka, Masaaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814939/ https://www.ncbi.nlm.nih.gov/pubmed/35178248 http://dx.doi.org/10.1515/tnsci-2022-0209 |
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