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Progression of Age-Related Macular Degeneration Among Individuals Homozygous for Risk Alleles on Chromosome 1 (CFH-CFHR5) or Chromosome 10 (ARMS2/HTRA1) or Both

IMPORTANCE: Age-related macular degeneration (AMD) is a common cause of irreversible vision loss among individuals older than 50 years. Although considerable advances have been made in our understanding of AMD genetics, the differential effects of major associated loci on disease manifestation and p...

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Detalles Bibliográficos
Autores principales: Schmitz-Valckenberg, Steffen, Fleckenstein, Monika, Zouache, Moussa A., Pfau, Maximilian, Pappas, Christian, Hageman, Jill L., Agrón, Elvira, Malley, Claire, Keenan, Tiarnan D. L., Chew, Emily Y., Hageman, Gregory S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814975/
https://www.ncbi.nlm.nih.gov/pubmed/35113155
http://dx.doi.org/10.1001/jamaophthalmol.2021.6072