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Progression of Age-Related Macular Degeneration Among Individuals Homozygous for Risk Alleles on Chromosome 1 (CFH-CFHR5) or Chromosome 10 (ARMS2/HTRA1) or Both
IMPORTANCE: Age-related macular degeneration (AMD) is a common cause of irreversible vision loss among individuals older than 50 years. Although considerable advances have been made in our understanding of AMD genetics, the differential effects of major associated loci on disease manifestation and p...
Autores principales: | Schmitz-Valckenberg, Steffen, Fleckenstein, Monika, Zouache, Moussa A., Pfau, Maximilian, Pappas, Christian, Hageman, Jill L., Agrón, Elvira, Malley, Claire, Keenan, Tiarnan D. L., Chew, Emily Y., Hageman, Gregory S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8814975/ https://www.ncbi.nlm.nih.gov/pubmed/35113155 http://dx.doi.org/10.1001/jamaophthalmol.2021.6072 |
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