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Long non-coding RNA TUG1 sponges microRNA-9 to protect podocytes from high glucose-induced apoptosis and mitochondrial dysfunction via SIRT1 upregulation

Podocyte apoptosis and mitochondrial dysfunction serve a major role in diabetic nephropathy progression. The present study revealed a molecular mechanism regulating podocyte apoptosis and mitochondrial dysfunction. In vitro models were established using conditionally immortalized mouse podocyte clon...

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Detalles Bibliográficos
Autores principales: Lei, Min, Ke, Guibao, Wang, Yan, Luo, Dan, Hu, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815052/
https://www.ncbi.nlm.nih.gov/pubmed/35222713
http://dx.doi.org/10.3892/etm.2022.11161