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Combined treatment with niclosamide ethanolamine and artemether combination improves type 1 diabetes via the targeting of liver mitochondria

Type 1 diabetes (T1D) is characterized by dysregulated blood glucose and liver metabolism. In previous studies, niclosamide ethanolamine salt (NEN) and artemether (Art) displayed significant hypoglycemic effects. However, their combined therapeutic effects on the liver in T1D have remained elusive....

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Detalles Bibliográficos
Autores principales: Weng, Wenci, Liu, Honghong, Sun, Zhijian, Zhou, Peng, Yu, Xuewen, Shao, Mumin, Han, Pengxun, Sun, Huili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815055/
https://www.ncbi.nlm.nih.gov/pubmed/35222716
http://dx.doi.org/10.3892/etm.2022.11164