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Direct Measurement of Interhelical DNA Repulsion and Attraction by Quantitative Cross-Linking

[Image: see text] To better understand the forces that mediate nucleic acid compaction in biology, we developed the disulfide cross-linking approach xHEED (X-linking of Helices to measure Electrostatic Effects at Distance) to measure the distance-dependent encounter frequency of two DNA helices in s...

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Detalles Bibliográficos
Autores principales: Hamilton, Ian, Gebala, Magdalena, Herschlag, Daniel, Russell, Rick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815069/
https://www.ncbi.nlm.nih.gov/pubmed/35073489
http://dx.doi.org/10.1021/jacs.1c11122