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PBK/TOPK Inhibitor Suppresses the Progression of Prolactinomas

BACKGROUND: Prolactinoma is the most common type of pituitary tumors, and its resultant tumor occupying and hormone disturbance greatly damage the health of patients. In this study, we investigated a protein kinase-PDZ Binding Kinase (PBK)/T-LAK Cell-Originated Protein Kinase (TOPK) as a candidate p...

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Detalles Bibliográficos
Autores principales: Zhu, Kejing, Cheng, Xueting, Wang, Shuman, Zhang, Hong, Zhang, Yu, Wang, Xiong, Chen, Yonggang, Wu, Jinhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815076/
https://www.ncbi.nlm.nih.gov/pubmed/35126305
http://dx.doi.org/10.3389/fendo.2021.706909