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N6-methyladenosine-dependent modification of circGARS acts as a new player that promotes SLE progression through the NF-κB/A20 axis

BACKGROUND: Certain circRNAs could be used as biomarkers to determine the risk of development and/or severity of systemic lupus erythematosus, and their new function in the regulation of gene expression has motivated us to investigate their role in SLE METHODS: Experimental methods including qRT-PCR...

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Detalles Bibliográficos
Autores principales: Zhao, Xingwang, Dong, Rui, Zhang, Longlong, Guo, Junkai, Shi, Ying, Ge, Lan, Wang, Juan, Song, Zhiqiang, Ni, Bing, You, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815128/
https://www.ncbi.nlm.nih.gov/pubmed/35120571
http://dx.doi.org/10.1186/s13075-022-02732-x