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Hypoxic stress disrupts HGF/Met signaling in human trophoblasts: implications for the pathogenesis of preeclampsia

BACKGROUND: Preeclampsia (PE), a placenta-associated pregnancy complication, is the leading cause of maternal and perinatal morbidity and mortality. Met/Erk signaling is inhibited in the placentas of patients with early-onset preeclampsia (E-PE), but the underlying mechanisms remain elusive. In this...

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Detalles Bibliográficos
Autores principales: Li, Guanlin, Wang, Yongqing, Cao, Guangming, Ma, Yeling, Li, Yu-Xia, Zhao, Yangyu, Shao, Xuan, Wang, Yan-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815204/
https://www.ncbi.nlm.nih.gov/pubmed/35114998
http://dx.doi.org/10.1186/s12929-022-00791-5