Cargando…
Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia
BACKGROUND: Chronic lymphocytic leukemia (CLL) is the most frequent, and still incurable, form of leukemia in the Western World. It is widely accepted that cancer results from an evolutionary process shaped by the acquisition of driver mutations which confer selective growth advantage to cells that...
Autores principales: | , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815240/ https://www.ncbi.nlm.nih.gov/pubmed/35120522 http://dx.doi.org/10.1186/s12943-022-01496-x |