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Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia

BACKGROUND: Chronic lymphocytic leukemia (CLL) is the most frequent, and still incurable, form of leukemia in the Western World. It is widely accepted that cancer results from an evolutionary process shaped by the acquisition of driver mutations which confer selective growth advantage to cells that...

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Detalles Bibliográficos
Autores principales:	Hortal, Alejandro M., Oeste, Clara L., Cifuentes, Claudia, Alcoceba, Miguel, Fernández-Pisonero, Isabel, Clavaín, Laura, Tercero, Rut, Mendoza, Pilar, Domínguez, Verónica, García-Flores, Marta, Pintado, Belén, Abia, David, García-Macías, Carmen, Navarro-Bailón, Almudena, Bustelo, Xosé R., González, Marcos, Alarcón, Balbino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815240/ https://www.ncbi.nlm.nih.gov/pubmed/35120522 http://dx.doi.org/10.1186/s12943-022-01496-x

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