Lyophilization provides long-term stability for a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine

Lipid nanoparticle (LNP)-formulated nucleoside-modified mRNA vaccines have proven to be very successful in the fight against the coronavirus disease 2019 (COVID-19) pandemic. They are effective, safe, and can be produced in large quantities. However, the long-term storage of mRNA-LNP vaccines withou...

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Detalles Bibliográficos
Autores principales: Muramatsu, Hiromi, Lam, Kieu, Bajusz, Csaba, Laczkó, Dorottya, Karikó, Katalin, Schreiner, Petra, Martin, Alan, Lutwyche, Peter, Heyes, James, Pardi, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815268/
https://www.ncbi.nlm.nih.gov/pubmed/35131437
http://dx.doi.org/10.1016/j.ymthe.2022.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815268/
https://www.ncbi.nlm.nih.gov/pubmed/35131437
http://dx.doi.org/10.1016/j.ymthe.2022.02.001

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