From GWAS to drug screening: repurposing antipsychotics for glioblastoma

BACKGROUND: Glioblastoma is currently an incurable cancer. Genome-wide association studies have demonstrated that 41 genetic variants are associated with glioblastoma and may provide an option for drug development. METHODS: We investigated FDA-approved antipsychotics for their potential treatment of...

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Detalles Bibliográficos
Autores principales: Lin, Wei-Zhi, Liu, Yen-Chun, Lee, Meng-Chang, Tang, Chi-Tun, Wu, Gwo-Jang, Chang, Yu-Tien, Chu, Chi-Ming, Shiau, Chia-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815269/
https://www.ncbi.nlm.nih.gov/pubmed/35120529
http://dx.doi.org/10.1186/s12967-021-03209-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815269/
https://www.ncbi.nlm.nih.gov/pubmed/35120529
http://dx.doi.org/10.1186/s12967-021-03209-2

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