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C. elegans as an in vivo model system for the phenotypic drug discovery for treating paraquat poisoning

BACKGROUND: Paraquat (PQ) is an effective and widely used herbicide and causes numerous fatalities by accidental or voluntary ingestion. However, neither the final cytotoxic mechanism nor effective treatments for PQ poisoning have been discovered. Phenotypic drug discovery (PDD), which does not rely...

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Detalles Bibliográficos
Autores principales: Ji, Peng, Li, Hongyuan, Jin, Yushan, Peng, Yinghua, Zhao, Lihui, Wang, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815376/
https://www.ncbi.nlm.nih.gov/pubmed/35178301
http://dx.doi.org/10.7717/peerj.12866