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C. elegans as an in vivo model system for the phenotypic drug discovery for treating paraquat poisoning
BACKGROUND: Paraquat (PQ) is an effective and widely used herbicide and causes numerous fatalities by accidental or voluntary ingestion. However, neither the final cytotoxic mechanism nor effective treatments for PQ poisoning have been discovered. Phenotypic drug discovery (PDD), which does not rely...
Autores principales: | Ji, Peng, Li, Hongyuan, Jin, Yushan, Peng, Yinghua, Zhao, Lihui, Wang, Xiaohui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815376/ https://www.ncbi.nlm.nih.gov/pubmed/35178301 http://dx.doi.org/10.7717/peerj.12866 |
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