Single Impact Injury of Vertebral Endplates Without Structural Disruption, Initiates Disc Degeneration Through Piezo1 Mediated Inflammation and Metabolism Dysfunction

In vitro experimental study. OBJECTIVE. To establish an axial impact injury model of intervertebral disc (IVD) and to investigate if a single impact injury without endplate structural disruption could initiate intervertebral disc degeneration (IDD), and what is the roles of Piezo1 in this process. S...

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Detalles Bibliográficos
Autores principales: Sun, Zhengang, Zheng, Xinfeng, Li, Songbo, Zeng, Baozhu, Yang, Jiaming, Ling, Zemin, Liu, Xizhe, Wei, Fuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815838/
https://www.ncbi.nlm.nih.gov/pubmed/34431832
http://dx.doi.org/10.1097/BRS.0000000000004203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815838/
https://www.ncbi.nlm.nih.gov/pubmed/34431832
http://dx.doi.org/10.1097/BRS.0000000000004203

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