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A novel pro-oxidant combination of resveratrol and copper reduces transplant related toxicities in patients receiving high dose melphalan for multiple myeloma (RESCU 001)

BACKGROUND: Transplant related toxicity is a major therapeutic challenge. We have previously reported that the toxicity of chemotherapy is largely not directly because of the drugs themselves; rather it is mainly due to DNA damage, apoptosis and hyper-inflammation triggered by cell-free chromatin pa...

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Detalles Bibliográficos
Autores principales: Agarwal, Anshul, Khandelwal, Aakanksha, Pal, Kavita, Khare, Naveen Kumar, Jadhav, Vishal, Gurjar, Murarilal, Punatar, Sachin, Gokarn, Anant, Bonda, Avinash, Nayak, Lingaraj, Kannan, Sadhana, Gota, Vikram, Khattry, Navin, Mittra, Indraneel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815866/
https://www.ncbi.nlm.nih.gov/pubmed/35120140
http://dx.doi.org/10.1371/journal.pone.0262212