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Mechanistic Insight Into Cadmium- and Zinc-Induced Inactivation of the Candida albicans Pif1 Helicase

Zinc and cadmium are environmental contaminants that can cause disease by affecting the activity of DNA-repair proteins. In this study, we investigated the effect of Zn(2+) and Cd(2+) on the Candida albicans Pif1, a DNA-repair helicase that plays a critical role in ensuring genomic stability. We sho...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Zhang, Qintao, Zhu, Xinting, Li, Dayu, Duan, Xiaolei, Jin, Jiao, Wang, Kejia, Xie, Yan, Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815974/
https://www.ncbi.nlm.nih.gov/pubmed/35127815
http://dx.doi.org/10.3389/fmolb.2021.778647