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Mechanistic Insight Into Cadmium- and Zinc-Induced Inactivation of the Candida albicans Pif1 Helicase
Zinc and cadmium are environmental contaminants that can cause disease by affecting the activity of DNA-repair proteins. In this study, we investigated the effect of Zn(2+) and Cd(2+) on the Candida albicans Pif1, a DNA-repair helicase that plays a critical role in ensuring genomic stability. We sho...
Autores principales: | Zhang, Bo, Zhang, Qintao, Zhu, Xinting, Li, Dayu, Duan, Xiaolei, Jin, Jiao, Wang, Kejia, Xie, Yan, Liu, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8815974/ https://www.ncbi.nlm.nih.gov/pubmed/35127815 http://dx.doi.org/10.3389/fmolb.2021.778647 |
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