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Extent, pattern, and prognostic value of MGMT promotor methylation: does it differ between glioblastoma and IDH-wildtype/TERT-mutated astrocytoma?

INTRODUCTION: The cIMPACT-NOW update 6 first introduced glioblastoma diagnosis based on the combination of IDH-wildtype (IDHwt) status and TERT promotor mutation (pTERTmut). In glioblastoma as defined by histopathology according to the WHO 2016 classification, MGMT promotor status is associated with...

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Detalles Bibliográficos
Autores principales: Teske, Nico, Karschnia, Philipp, Weller, Jonathan, Siller, Sebastian, Dorostkar, Mario M., Herms, Jochen, von Baumgarten, Louisa, Tonn, Joerg Christian, Thon, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816375/
https://www.ncbi.nlm.nih.gov/pubmed/34902093
http://dx.doi.org/10.1007/s11060-021-03912-6