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Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes

Cell surface receptors control how cells respond to their environment. Many cell surface receptors recycle from endosomes to the plasma membrane via a recently discovered pathway, which includes sorting-nexin SNX17, Retriever, WASH, and CCC complexes. Here, using mammalian cells, we discover that PI...

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Detalles Bibliográficos
Autores principales: Giridharan, Sai Srinivas Panapakkam, Luo, Guangming, Rivero-Rios, Pilar, Steinfeld, Noah, Tronchere, Helene, Singla, Amika, Burstein, Ezra, Billadeau, Daniel D, Sutton, Michael A, Weisman, Lois S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816382/
https://www.ncbi.nlm.nih.gov/pubmed/35040777
http://dx.doi.org/10.7554/eLife.69709