Empagliflozin Enhances Autophagy, Mitochondrial Biogenesis, and Antioxidant Defense and Ameliorates Renal Ischemia/Reperfusion in Nondiabetic Rats

BACKGROUND: Recent meta-analyses have shown that sodium-glucose cotransporter 2 (SGLT-2) inhibitors alleviate chronic kidney disease and acute kidney injury in diabetic patients. In this study, we aimed to investigate the effect of empagliflozin on renal ischemia/reperfusion (I/R) in nondiabetic rat...

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Detalles Bibliográficos
Autores principales: Ala, Moein, Khoshdel, Mohammad Reza Fallahpour, Dehpour, Ahmad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816566/
https://www.ncbi.nlm.nih.gov/pubmed/35126806
http://dx.doi.org/10.1155/2022/1197061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816566/
https://www.ncbi.nlm.nih.gov/pubmed/35126806
http://dx.doi.org/10.1155/2022/1197061

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