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Chidamide Suppresses the Growth of Cholangiocarcinoma by Inhibiting HDAC3 and Promoting FOXO1 Acetylation

Inhibitors for histone deacetylases (HDACs) have been identified as epigenetic drug targets to treat a variety of malignancies through several molecular mechanisms. The present study is aimed at investigating the mechanism underlying the possible antitumor effect of the HDAC inhibitor chidamide (CDM...

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Detalles Bibliográficos
Autores principales: Li, Yongpan, Zheng, Jujia, Huo, Qiang, Chen, Zhongchao, Chen, Jun, Xu, Xiangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816583/
https://www.ncbi.nlm.nih.gov/pubmed/35126526
http://dx.doi.org/10.1155/2022/3632549