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lnc-MRGPRF-6:1 Promotes M1 Polarization of Macrophage and Inflammatory Response through the TLR4-MyD88-MAPK Pathway

BACKGROUND: Macrophage-mediated inflammation plays an essential role in the development of atherosclerosis (AS). Long noncoding RNAs (lncRNAs), as crucial regulators, participate in this process. We identified that lnc-MRGPRF-6:1 was significantly upregulated in the plasma exosomes of coronary ather...

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Detalles Bibliográficos
Autores principales: Hu, Dan, Wang, Yuzhong, You, Zhihuan, Lu, Yingfei, Liang, Caihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816599/
https://www.ncbi.nlm.nih.gov/pubmed/35125964
http://dx.doi.org/10.1155/2022/6979117